Can I use List in DESelect Segment?

when working with subscriber data in salesforce marketing cloud, it’s important to understand the difference between lists and data extensions this article explains why deselect segment supports only data extensions, and not lists, by highlighting their key differences and advantages salesforce marketing cloud offers two primary methods for storing subscriber data lists data extensions what are list? while lists are suitable for simpler use cases or smaller scale email marketing programs, they come with a number of limitations scalability lists are not ideal for handling large volumes of data or complex segmentation logic flexibility lists are limited in terms of custom attributes and do not support advanced data modeling salesforce itself recommends using data extensions over lists, especially for customers using email studio, automation studio, or journey builder because deselect segment is designed to empower users with scalable, flexible, and enterprise ready segmentation capabilities, we’ve chosen to exclusively support data extensions what are data extensions? data extensions (des) are tables within sfmc that store data in a more customizable and relational way than lists data extensions can contain any data type, including subscriber information, behavioral data, purchase history, or custom attributes with deselect segment, you can easily segment, join, and filter across multiple data extensions—making them ideal for dynamic, real time audience creation